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Friedrich Simmel (Technische Universität München)

The research conducted by Prof. Simmel revolves around bionanotechnology and the physics of synthetic biological systems. His particular areas of interest include artificial molecular machines, the design of artificial biochemical circuits and self-organisation of complex systems. He has been Chair of Physics of Synthetic Biological Systems (E14) at TUM since 2007. Since 2013, Prof. Simmel has been a member of acatech - the National Academy of Science and Engineering.

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Kirsten Jung (Ludwig-Maximilians-Universität München)

Research in the Jung lab focuses on the elucidation of the molecular mechanisms of stimulus perception by membrane-integrated receptors. Moreover, they are studying the complexity of regulatory networks in correlation with phenotypic heterogeneity. Last, but not least, they are investigating translation regulation and synthetic protein modifications.

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Michael Hecht (Princeton University)

Research in the Hecht group focuses in two areas: Synthetic Biology and Alzheimer's Disease. Although these fields may seem quite different, they explore two facets of the same problem. Synthetic biology requires an ability to devise novel proteins, which ultimately comes down to designing amino acid sequences that fold into a specific 3-dimensional structure. Conversely, probing the molecular underpinnings of Alzheimer’s disease requires an understanding of how sequences fail to fold into globular protein structures, but instead misfold into oligomeric or fibrillar structures.

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Kathrin Lang (Technische Universität München)

Professor Lang conducts research in the interdisciplinary area of chemical biology, applying concepts from organic chemistry to develop new tools to study fundamental biological questions. Her research focuses on the targeted chemical synthesis of new artificial biomolecules (amino acids, proteins, nucleotides, oligonucleotides) tailored to investigate and manipulate complex cellular processes in in vitro and in vivo biological systems.

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James Murray (Imperial College London)

Murrays group is working on structural and synthetic biology of photosynthesis. Their topics cover carbon fixation in plants and cyanobacteria and investigation in the structural basis of nitrogenase resistance to oxygen, which is important for biotechnological applications of this enzyme. Additionally they investigate ways to mimic the catalytic activity of photosystem II by engineering other proteins to bind a cluster of metal atoms in a similar way to the natural system.

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Pamela Silver (Harvard Medical School)

The Silver Lab develops principles for building synthetic cells that act as sensors, memory devices, bio-computers, producers of high value commodities and energy from the sun, and they build novel subsystems such as proteins with designed properties for therapeutic use.
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